Experienced Clinical Cases

Real-world clinical biochemistry cases I've encountered and analyzed.

Hepato-Renal Syndrome
A case study on the biochemical aspects of hepato-renal syndrome

This case explores the complex relationship between liver dysfunction and subsequent kidney impairment, with a focus on the biochemical markers and diagnostic challenges.

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Gammapathy of Renal Significance
A case study on monoclonal gammopathy affecting renal function

This case examines how monoclonal gammopathies can lead to kidney damage through various mechanisms, with emphasis on laboratory findings and diagnostic approaches.

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B12 Deficiency and HPLC
A case study on vitamin B12 deficiency detection using HPLC

This case discusses the application of High-Performance Liquid Chromatography (HPLC) in diagnosing vitamin B12 deficiency, highlighting the analytical techniques and clinical correlations.

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Fully Compensated Metabolic Acidosis
A case study on acid-base balance and compensation mechanisms

This case explores the physiological mechanisms of compensation in metabolic acidosis, with detailed analysis of blood gas parameters and electrolyte balance.

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Hook Effect
A case study on the hook effect in immunoassays

This case examines the hook effect phenomenon in immunoassays, where extremely high analyte concentrations can paradoxically lead to falsely low results, with implications for clinical diagnosis.

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Hb Variant HPLC
A case study on hemoglobin variants detected by HPLC

This case focuses on the detection and characterization of hemoglobin variants using High-Performance Liquid Chromatography, with emphasis on interpretation of chromatograms and clinical significance.

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HELP Syndrome - Paralytic Ileus
A case study on HELP syndrome with paralytic ileus

This case discusses the biochemical aspects of HELP syndrome (Hemolysis, Elevated Liver enzymes, Low Platelets) complicated by paralytic ileus, with focus on diagnostic markers and clinical management.

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